Krill Oil Effect on Cardiovascular Risk Factors


Scientists conducted a randomized, double-blind controlled cross-over trial over a number of weeks. The aim was to evaluate the effects of krill oil supplementation on endothelial function and other cardiac risk considerations. This was specific to patients with type-2 diabetes and the effects that krill oil had on blood glucose control.

The outcomes assessed during the trial were:

  • Endothelial function
  • Blood lipids
  • Glucose
  • Glycated hemoglobin
  • Serum antioxidant level
  • C peptide
  • Calculated Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) scores.

The volunteers were randomized to take either olive oil or krill oil supplementation for four consecutive weeks. After the four weeks they then underwent a two week washout period. The participants then changed over to the other supplementation for a further four weeks. After this time, participants were presented with an option to take krill supplementation for another 17 weeks. During the trial, testing occurred at three points:

  1. Baseline
  2. After first supplementation
  3. After second supplementation

The Conclusion

What the scientists deducted from this trial was Krill oil may lead to a reasonable improvement of cardiovascular risks. This was specifically in regard to endothelial dysfunction and HDL in overweight patients suffering with type-2 diabetes.

http://www.ncbi.nlm.nih.gov/pubmed/26504524

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