Effects of Krill Oil on Mitochondrial Energetic Metabolism

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Over the years, numerous studies have looked at the role of dietary fats in the pathogenesis (development of a disease) of fatty liver (hepatic steatosis). Studies demonstrate how a diet that is high in fat is able to induce an excess of glucose in the bloodstream (hyperglycemia), excess levels of insulin circulating in the blood (hyperinsulinemia), obesity, and also non-alcoholic fatty liver disease (NAFLD).

Research has also shown how krill oil (a dietary supplement of n-3 PUFAs), can actually improve lipid and glucose metabolism. This demonstrates a potential to protect the effects against hepatic steatosis.

The study was conducted on lab rats. Scientists looked at the effects of krill oil on mitochondrial energetic metabolism in the animals that were fed a high-fat diet. They were divided into three groups:

  1. Standard diet (control group)
  2. Diet with 35% fat (HF group)
  3. High-fat diet supplemented with 2.5% krill oil (HF+KO group)

The trial lasted for four weeks. The conclusion was that krill oil burns off excess fat introduced into the diet. On the whole, krill oil, it seems, counters the negative effects of a HF diet on mitochondrial energetic metabolism.


Krill Oil Ameliorates Mitochondrial Dysfunctions in Rats Treated with High-Fat Diet.


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